Publications

Key Publications

  • Zundler, S., Gunther, C., Kremer, A. E., Zaiss, M. M., Rothhammer, V., & Neurath, M. F. (2022). Gut immune cell trafficking: inter-organ communication and immune-mediated inflammation. Nat Rev Gastroenterol Hepatol. doi:10.1038/s41575-022-00663-1
  • Schmidt, S., Luecken, M. D., Trumbach, D., Hembach, S., Niedermeier, K. M., Wenck, N., Pflugler, K., Stautner, C., Bottcher, A., Lickert, H., Ramirez-Suastegui, C., Ahmad, R., Ziller, M. J., Fitzgerald, J. C., Ruf, V., van de Berg, W. D. J., Jonker, A. J., Gasser, T., Winner, B., Winkler, J., Vogt Weisenhorn, D. M., Giesert, F., Theis, F. J., & Wurst, W. (2022). Primary cilia and SHH signaling impairments in human and mouse models of Parkinson’s disease. Nat Commun, 13(1), 4819. doi:10.1038/s41467-022-32229-9
  • Schmalzl, A., Leupold, T., Kreiss, L., Waldner, M., Schurmann, S., Neurath, M. F., Becker, C., & Wirtz, S. (2022). Interferon regulatory factor 1 (IRF-1) promotes intestinal group 3 innate lymphoid responses during Citrobacter rodentium infection. Nat Commun, 13(1), 5730. doi:10.1038/s41467-022-33326-5
  • Mackensen, A., Muller, F., Mougiakakos, D., Boltz, S., Wilhelm, A., Aigner, M., Volkl, S., Simon, D., Kleyer, A., Munoz, L., Kretschmann, S., Kharboutli, S., Gary, R., Reimann, H., Rosler, W., Uderhardt, S., Bang, H., Herrmann, M., Ekici, A. B., Buettner, C., Habenicht, K. M., Winkler, T. H., Kronke, G., & Schett, G. (2022). Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus. Nat Med, 28(10), 2124-2132. doi:10.1038/s41591-022-02017-5
  • Krach, F., Wheeler, E. C., Regensburger, M., Boerstler, T., Wend, H., Vu, A. Q., Wang, R., Reischl, S., Boldt, K., Batra, R., Aigner, S., Ravits, J., Winkler, J., Yeo, G. W., & Winner, B. (2022). Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis. Acta Neuropathol, 144(3), 413-435. doi:10.1007/s00401-022-02450-3

2023

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  • Stolzer, I., Scherer, E., Süß, P., Rothhammer, V., Winner, B., Neurath, M. F., & Günther, C. (2023). Impact of Microbiome-Brain Communication on Neuroinflammation and Neurodegeneration. International journal of molecular sciences, 24(19), 14925. https://doi.org/10.3390/ijms241914925

2022

  • Zundler, S., Gunther, C., Kremer, A. E., Zaiss, M. M., Rothhammer, V., & Neurath, M. F. (2022). Gut immune cell trafficking: inter-organ communication and immune-mediated inflammation. Nat Rev Gastroenterol Hepatol. doi:10.1038/s41575-022-00663-1
  • Zhang, J., & Wirtz, S. (2022). Does Pyroptosis Play a Role in Inflammasome-Related Disorders? Int J Mol Sci, 23(18). doi:10.3390/ijms231810453
  • Yu, Y. Q., Gamez-Belmonte, R., Patankar, J. V., Liebing, E., & Becker, C. (2022). The Role of Programmed Necrosis in Colorectal Cancer. Cancers (Basel), 14(17). doi:10.3390/cancers14174295
  • Wilm, F., Fragoso, M., Marzahl, C., Qiu, J., Puget, C., Diehl, L., Bertram, C. A., Klopfleisch, R., Maier, A., Breininger, K., & Aubreville, M. (2022). Pan-tumor CAnine cuTaneous Cancer Histology (CATCH) dataset. Sci Data, 9(1), 588. doi:10.1038/s41597-022-01692-w
  • Wilferth, T., Muller, M., Gast, L. V., Ruck, L., Meyerspeer, M., Lopez Kolkovsky, A. L., Uder, M., Dorfler, A., & Nagel, A. M. (2022). Motion-corrected (23) Na MRI of the human brain using interleaved (1) H 3D navigator images. Magn Reson Med, 88(1), 309-321. doi:10.1002/mrm.29221
  • Wilferth, T., Mennecke, A., Gast, L. V., Lachner, S., Muller, M., Rothhammer, V., Huhn, K., Uder, M., Doerfler, A., Nagel, A. M., & Schmidt, M. (2022). Quantitative 7T sodium magnetic resonance imaging of the human brain using a 32-channel phased-array head coil: Application to patients with secondary progressive multiple sclerosis. NMR Biomed, 35(12), e4806. doi:10.1002/nbm.4806
  • Wen, J., Lyu, P., Stolzer, I., Xu, J., Giessl, A., Lin, Z., Andreev, D., Kachler, K., Song, R., Meng, X., Cao, S., Guggino, G., Ciccia, F., Gunther, C., Schett, G., & Bozec, A. (2022). Epithelial HIF2alpha expression induces intestinal barrier dysfunction and exacerbation of arthritis. Ann Rheum Dis. doi:10.1136/annrheumdis-2021-222035
  • Wagner, F., Thies, M., Gu, M., Huang, Y., Pechmann, S., Patwari, M., Ploner, S., Aust, O., Uderhardt, S., Schett, G., Christiansen, S., & Maier, A. (2022). Ultralow-parameter denoising: Trainable bilateral filter layers in computed tomography. Med Phys, 49(8), 5107-5120. doi:10.1002/mp.15718
  • Voskens, C., Stoica, D., Rosenberg, M., Vitali, F., Zundler, S., Ganslmayer, M., Knott, H., Wiesinger, M., Wunder, J., Kummer, M., Siegmund, B., Schnoy, E., Rath, T., Hartmann, A., Hackstein, H., Schuler-Thurner, B., Berking, C., Schuler, G., Atreya, R., & Neurath, M. F. (2022). Autologous regulatory T-cell transfer in refractory ulcerative colitis with concomitant primary sclerosing cholangitis. Gut, 72(1), 49-53. doi:10.1136/gutjnl-2022-327075
  • Varela, F., Symowski, C., Pollock, J., Wirtz, S., & Voehringer, D. (2022). IL-4/IL-13-producing ILC2s are required for timely control of intestinal helminth infection in mice. Eur J Immunol, 52(12), 1925-1933. doi:10.1002/eji.202249892
  • Utz, K. S., Kohl, Z., Marterstock, D. C., Doerfler, A., Winkler, J., Schmidt, M., & Regensburger, M. (2022). Neuropsychology and MRI correlates of neurodegeneration in SPG11 hereditary spastic paraplegia. Orphanet J Rare Dis, 17(1), 301. doi:10.1186/s13023-022-02451-1
  • Tisch, N., Mogler, C., Stojanovic, A., Luck, R., Korhonen, E. A., Ellerkmann, A., Adler, H., Singhal, M., Schermann, G., Erkert, L., Patankar, J. V., Karakatsani, A., Scherr, A. L., Fuchs, Y., Cerwenka, A., Wirtz, S., Kohler, B. C., Augustin, H. G., Becker, C., Schmidt, T., & Ruiz de Almodovar, C. (2022). Caspase-8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice. EMBO Mol Med, 14(6), e14121. doi:10.15252/emmm.202114121
  • Stolzer, I., Schickedanz, L., Chiriac, M. T., Lopez-Posadas, R., Grassl, G. A., Mattner, J., Wirtz, S., Winner, B., Neurath, M. F., & Gunther, C. (2022). STAT1 coordinates intestinal epithelial cell death during gastrointestinal infection upstream of Caspase-8. Mucosal Immunol, 15(1), 130-142. doi:10.1038/s41385-021-00450-2
  • Stern, S., Lau, S., Manole, A., Rosh, I., Percia, M. M., Ben Ezer, R., Shokhirev, M. N., Qiu, F., Schafer, S., Mansour, A. A., Mangan, K. P., Stern, T., Ofer, P., Stern, Y., Diniz Mendes, A. P., Djamus, J., Moore, L. R., Nayak, R., Laufer, S. H., Aicher, A., Rhee, A., Wong, T. L., Nguyen, T., Linker, S. B., Winner, B., Freitas, B. C., Jones, E., Sagi, I., Bardy, C., Brice, A., Winkler, J., Marchetto, M. C., & Gage, F. H. (2022). Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients. NPJ Parkinsons Dis, 8(1), 103. doi:10.1038/s41531-022-00366-z
  • Sprugel, M. I., Sembill, J. A., Kremer, S., Gerner, S. T., Knott, M., Hock, S., Engelhorn, T., Dorfler, A., Huttner, H. B., & Schwab, S. (2022). Evaluation of Functional Recovery Following Thrombectomy in Patients With Large Vessel Occlusion and Prestroke Disability. JAMA Netw Open, 5(8), e2227139. doi:10.1001/jamanetworkopen.2022.27139
  • Simon, D., Tascilar, K., Fagni, F., Kleyer, A., Kronke, G., Meder, C., Dietrich, P., Orlemann, T., Mossner, J., Taubmann, J., Mutlu, M. Y., Knitza, J., Kemenes, S., Liphardt, A. M., Schonau, V., Bohr, D., Schuster, L., Hartmann, F., Minopoulou, I., Leppkes, M., Ramming, A., Pachowsky, M., Schuch, F., Ronneberger, M., Kleinert, S., Hueber, A. J., Manger, K., Manger, B., Atreya, R., Berking, C., Sticherling, M., Neurath, M. F., & Schett, G. (2022). Intensity and longevity of SARS-CoV-2 vaccination response in patients with immune-mediated inflammatory disease: a prospective cohort study. Lancet Rheumatol, 4(9), e614-e625. doi:10.1016/S2665-9913(22)00191-6
  • Silvin, A., Uderhardt, S., Piot, C., Da Mesquita, S., Yang, K., Geirsdottir, L., Mulder, K., Eyal, D., Liu, Z., Bridlance, C., Thion, M. S., Zhang, X. M., Kong, W. T., Deloger, M., Fontes, V., Weiner, A., Ee, R., Dress, R., Hang, J. W., Balachander, A., Chakarov, S., Malleret, B., Dunsmore, G., Cexus, O., Chen, J., Garel, S., Dutertre, C. A., Amit, I., Kipnis, J., & Ginhoux, F. (2022). Dual ontogeny of disease-associated microglia and disease inflammatory macrophages in aging and neurodegeneration. Immunity, 55(8), 1448-1465 e1446. doi:10.1016/j.immuni.2022.07.004
  • Schweda, A., Becker, E., Wiendl, M., Atreya, R., Atreya, I., Muller, T. M., Neurath, M. F., & Zundler, S. (2022). Etrolizumab-s Does Not Induce Residual Trafficking of Regulatory T Cells. Inflamm Bowel Dis, 28(11), 1746-1755. doi:10.1093/ibd/izac137
  • Schwarz, H., Bassler, S., Balta, D., Socher, E., Zunke, F., & Arnold, P. (2022). The role of triggering receptor expressed on myeloid cells 2 in Parkinson’s disease and other neurodegenerative disorders. Behav Brain Res, 433, 113977. doi:10.1016/j.bbr.2022.113977
  • Schmidt, S., Luecken, M. D., Trumbach, D., Hembach, S., Niedermeier, K. M., Wenck, N., Pflugler, K., Stautner, C., Bottcher, A., Lickert, H., Ramirez-Suastegui, C., Ahmad, R., Ziller, M. J., Fitzgerald, J. C., Ruf, V., van de Berg, W. D. J., Jonker, A. J., Gasser, T., Winner, B., Winkler, J., Vogt Weisenhorn, D. M., Giesert, F., Theis, F. J., & Wurst, W. (2022). Primary cilia and SHH signaling impairments in human and mouse models of Parkinson’s disease. Nat Commun, 13(1), 4819. doi:10.1038/s41467-022-32229-9
  • Schmalzl, A., Leupold, T., Kreiss, L., Waldner, M., Schurmann, S., Neurath, M. F., Becker, C., & Wirtz, S. (2022). Interferon regulatory factor 1 (IRF-1) promotes intestinal group 3 innate lymphoid responses during Citrobacter rodentium infection. Nat Commun, 13(1), 5730. doi:10.1038/s41467-022-33326-5
  • Rizo, T., Gebhardt, L., Riedlberger, J., Eberhardt, E., Fester, L., Alansary, D., Winkler, J., Turan, S., Arnold, P., Niemeyer, B. A., Fischer, M. J. M., & Winner, B. (2022). Store-operated calcium entry is reduced in spastin-linked hereditary spastic paraplegia. Brain, 145(9), 3131-3146. doi:10.1093/brain/awac122
  • Reljic, D., Herrmann, H. J., Jakobs, B., Dieterich, W., Mougiakakos, D., Neurath, M. F., & Zopf, Y. (2022). Feasibility, Safety, and Preliminary Efficacy of Very Low-Volume Interval Training in Advanced Cancer Patients. Med Sci Sports Exerc, 54(11), 1817-1830. doi:10.1249/MSS.0000000000002989
  • Reichmann, H., Csoti, I., Koschel, J., Lorenzl, S., Schrader, C., Winkler, J., & Wullner, U. (2022). Life style and Parkinson’s disease. J Neural Transm (Vienna), 129(9), 1235-1245. doi:10.1007/s00702-022-02509-1
  • Regensburger, M., Spatz, I. T., Ollenschlager, M., Martindale, C. F., Lindeburg, P., Kohl, Z., Eskofier, B., Klucken, J., Schule, R., Klebe, S., Winkler, J., & Gassner, H. (2022). Inertial Gait Sensors to Measure Mobility and Functioning in Hereditary Spastic Paraplegia: A Cross-Sectional Multicenter Clinical Study. Neurology, 99(10), e1079-1089. doi:10.1212/WNL.0000000000200819
  • Qiu, J., Oppelt, M. P., Nissen, M., Anneken, L., Breininger, K., & Eskofier, B. (2022). Improving Deep Learning-based Cardiac Abnormality Detection in 12-Lead ECG with Data Augmentation. Annu Int Conf IEEE Eng Med Biol Soc, 2022, 945-949. doi:10.1109/EMBC48229.2022.9871969
  • Prieto Huarcaya, S., Drobny, A., Marques, A. R. A., Di Spiezio, A., Dobert, J. P., Balta, D., Werner, C., Rizo, T., Gallwitz, L., Bub, S., Stojkovska, I., Belur, N. R., Fogh, J., Mazzulli, J. R., Xiang, W., Fulzele, A., Dejung, M., Sauer, M., Winner, B., Rose-John, S., Arnold, P., Saftig, P., & Zunke, F. (2022). Recombinant pro-CTSD (cathepsin D) enhances SNCA/alpha-Synuclein degradation in alpha-Synucleinopathy models. Autophagy, 18(5), 1127-1151. doi:10.1080/15548627.2022.2045534
  • Pieger, K., Schmitt, V., Gauer, C., Giessl, N., Prots, I., Winner, B., Winkler, J., Brandstatter, J. H., & Xiang, W. (2022). Translocation of Distinct Alpha Synuclein Species from the Nucleus to Neuronal Processes during Neuronal Differentiation. Biomolecules, 12(8). doi:10.3390/biom12081108
  • Peyrin-Biroulet, L., Arkkila, P., Armuzzi, A., Danese, S., Guardiola, J., Jahnsen, J., Lees, C., Louis, E., Lukas, M., Reinisch, W., Roblin, X., Jang, M., Byun, H. G., Kim, D. H., Lee, S. J., & Atreya, R. (2022). Comparative efficacy and safety of infliximab and vedolizumab therapy in patients with inflammatory bowel disease: a systematic review and meta-analysis. BMC Gastroenterol, 22(1), 291. doi:10.1186/s12876-022-02347-1
  • Ollenschlager, M., Kuderle, A., Mehringer, W., Seifer, A. K., Winkler, J., Gassner, H., Kluge, F., & Eskofier, B. M. (2022). MaD GUI: An Open-Source Python Package for Annotation and Analysis of Time-Series Data. Sensors (Basel), 22(15). doi:10.3390/s22155849
  • Monteleone, G., Stolfi, C., Marafini, I., Atreya, R., & Neurath, M. F. (2022). Smad7 Antisense Oligonucleotide-Based Therapy in Crohn’s Disease: Is it Time to Re-Evaluate? Mol Diagn Ther, 26(5), 477-481. doi:10.1007/s40291-022-00606-1
  • Mishra, P., Verma, V. K., Barman, L., Sharma, J., Gupta, P., Mohan, A., & Arya, D. S. (2022). Correlation of serum amyloid A1 and interleukin-1beta in response to anti-tubercular therapy. Am J Med Sci, 364(3), 316-326. doi:10.1016/j.amjms.2021.12.014
  • Mennecke, A., Khakzar, K. M., German, A., Herz, K., Fabian, M. S., Liebert, A., Blumcke, I., Kasper, B. S., Nagel, A. M., Laun, F. B., Schmidt, M., Winkler, J., Dorfler, A., & Zaiss, M. (2022). 7 tricks for 7 T CEST: Improving the reproducibility of multipool evaluation provides insights into the effects of age and the early stages of Parkinson’s disease. NMR Biomed, e4717. doi:10.1002/nbm.4717
  • Masanetz, R. K., Winkler, J., Winner, B., Gunther, C., & Suss, P. (2022). The Gut-Immune-Brain Axis: An Important Route for Neuropsychiatric Morbidity in Inflammatory Bowel Disease. Int J Mol Sci, 23(19). doi:10.3390/ijms231911111
  • Marzahl, C., Hill, J., Stayt, J., Bienzle, D., Welker, L., Wilm, F., Voigt, J., Aubreville, M., Maier, A., Klopfleisch, R., Breininger, K., & Bertram, C. A. (2022). Inter-species cell detection – datasets on pulmonary hemosiderophages in equine, human and feline specimens. Sci Data, 9(1), 269. doi:10.1038/s41597-022-01389-0
  • Martinez-Sanchez, L. D. C., Ngo, P. A., Pradhan, R., Becker, L. S., Boehringer, D., Soteriou, D., Kubankova, M., Schweitzer, C., Koch, T., Thonn, V., Erkert, L., Stolzer, I., Gunther, C., Becker, C., Weigmann, B., Klewer, M., Daniel, C., Amann, K., Tenzer, S., Atreya, R., Bergo, M., Brakebusch, C., Watson, A. J. M., Guck, J., Fabry, B., Atreya, I., Neurath, M. F., & Lopez-Posadas, R. (2022). Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation. Gut. doi:10.1136/gutjnl-2021-325520
  • Malhotra, S., Mani, K., Lodha, R., Bakhshi, S., Mathur, V. P., Gupta, P., Kedia, S., Sankar, M. J., Kumar, P., Kumar, A., H, V., Ahuja, V., Sinha, S., Guleria, R., Dua, A., Ahmad, S., Upadhyay, A. D., Sati, H. C., Mani, K., Lokade, A. K., Devi, K. P., Johnson, R. M., Gowthaman, K., Kumari, M., Singh, R., Kalra, D., Swetambri, Vasudha, Sharma, S., Singh, A., Sharma, V., Kanswal, S., Sharma, R., Giri, T., Rajput, S., Mehra, G., Sharma, A., Madan, D., Singh, M., Gupta, A., Sharma, S., Sachdeva, S., Kumar, M., Sachin, Singh, A. K., Gohar, N., Kumar, R., Kanojia, N., Singhania, J., Dubey, R., Shukla, S., G, A., Sarkar, S., Gupta, I., Rai, S., Tummala, S., Reddy, T., Vadodaria, V., Sharma, A., Gupta, A., Vats, M., Deori, T. J., Jaiswal, A., & Pandit, S. (2022). COVID-19 infection, and reinfection, and vaccine effectiveness against symptomatic infection among health care workers in the setting of omicron variant transmission in New Delhi, India. Lancet Reg Health Southeast Asia, 3, 100023. doi:10.1016/j.lansea.2022.100023
  • Mackensen, A., Muller, F., Mougiakakos, D., Boltz, S., Wilhelm, A., Aigner, M., Volkl, S., Simon, D., Kleyer, A., Munoz, L., Kretschmann, S., Kharboutli, S., Gary, R., Reimann, H., Rosler, W., Uderhardt, S., Bang, H., Herrmann, M., Ekici, A. B., Buettner, C., Habenicht, K. M., Winkler, T. H., Kronke, G., & Schett, G. (2022). Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus. Nat Med, 28(10), 2124-2132. doi:10.1038/s41591-022-02017-5
  • Linnerbauer, M., Losslein, L., Vandrey, O., Tsaktanis, T., Beer, A., Naumann, U. J., Panier, F., Beyer, T., Nirschl, L., Kuramatsu, J. B., Winkler, J., Quintana, F. J., & Rothhammer, V. (2022). Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation. JCI Insight, 7(7). doi:10.1172/jci.insight.154824
  • Leupold, L., Sigutova, V., Gerasimova, E., Regensburger, M., Zundler, S., Zunke, F., Xiang, W., Winner, B., & Prots, I. (2022). The Quest for Anti-alpha-Synuclein Antibody Specificity-Lessons Learnt From Flow Cytometry Analysis. Front Neurol, 13, 869103. doi:10.3389/fneur.2022.869103
  • Leppkes, M., & Neurath, M. F. (2022). Rear Window-What Can the Gut Tell Us About Long-COVID? Gastroenterology, 163(2), 376-378. doi:10.1053/j.gastro.2022.05.044
  • Leppkes, M., Lindemann, A., Gosswein, S., Paulus, S., Roth, D., Hartung, A., Liebing, E., Zundler, S., Gonzalez-Acera, M., Patankar, J. V., Mascia, F., Scheibe, K., Hoffmann, M., Uderhardt, S., Schauer, C., Foersch, S., Neufert, C., Vieth, M., Schett, G., Atreya, R., Kuhl, A. A., Bleich, A., Becker, C., Herrmann, M., & Neurath, M. F. (2022). Neutrophils prevent rectal bleeding in ulcerative colitis by peptidyl-arginine deiminase-4-dependent immunothrombosis. Gut, 71(12), 2414-2429. doi:10.1136/gutjnl-2021-324725
  • Kuramatsu, J. B., Gerner, S. T., Ziai, W., Bardutzky, J., Sembill, J. A., Sprugel, M. I., Mrochen, A., Kolbl, K., Ram, M., Avadhani, R., Falcone, G. J., Selim, M. H., Lioutas, V. A., Endres, M., Zweynert, S., Vajkoczy, P., Ringleb, P. A., Purrucker, J. C., Volkmann, J., Neugebauer, H., Erbguth, F., Schellinger, P. D., Knappe, U. J., Fink, G. R., Dohmen, C., Minnerup, J., Reichmann, H., Schneider, H., Rother, J., Reimann, G., Schwarz, M., Bazner, H., Classen, J., Michalski, D., Witte, O. W., Gunther, A., Hamann, G. F., Lucking, H., Dorfler, A., Ishfaq, M. F., Chang, J. J., Testai, F. D., Woo, D., Alexandrov, A. V., Staykov, D., Goyal, N., Tsivgoulis, G., Sheth, K. N., Awad, I. A., Schwab, S., Hanley, D. F., Huttner, H. B., & Collaborators. (2022). Association of Intraventricular Fibrinolysis With Clinical Outcomes in Intracerebral Hemorrhage: An Individual Participant Data Meta-Analysis. Stroke, 53(9), 2876-2886. doi:10.1161/STROKEAHA.121.038455
  • Kucharzik, T., Atreya, R., Bachmann, O., Baumgart, D. C., Daebritz, J., Helwig, U., Janschek, J., Kienle, P., Langhorst, J., Mudter, J., Schmidt, C., Schreyer, A. G., Vieth, M., Wessling, J., & Maaser, C. (2022). [Position paper on reporting of intestinal ultrasound findings in patients with inflammatory bowel disease]. Z Gastroenterol, 60(6), 978-990. doi:10.1055/a-1801-0170
  • Kreiss, L., Thoma, O. M., Lemire, S., Lechner, K., Carle, B., Dilipkumar, A., Kunert, T., Scheibe, K., Heichler, C., Merten, A. L., Weigmann, B., Neufert, C., Hildner, K., Vieth, M., Neurath, M. F., Friedrich, O., Schurmann, S., & Waldner, M. J. (2022). Label-Free Characterization and Quantification of Mucosal Inflammation in Common Murine Colitis Models With Multiphoton Imaging. Inflamm Bowel Dis, 28(11), 1637-1646. doi:10.1093/ibd/izac114
  • Kreiss, L., Ganzleben, I., Muhlberg, A., Ritter, P., Schneidereit, D., Becker, C., Neurath, M. F., Friedrich, O., Schurmann, S., & Waldner, M. (2022). Label-free analysis of inflammatory tissue remodeling in murine lung tissue based on multiphoton microscopy, Raman spectroscopy and machine learning. J Biophotonics, 15(9), e202200073. doi:10.1002/jbio.202200073
  • Krach, F., Wheeler, E. C., Regensburger, M., Boerstler, T., Wend, H., Vu, A. Q., Wang, R., Reischl, S., Boldt, K., Batra, R., Aigner, S., Ravits, J., Winkler, J., Yeo, G. W., & Winner, B. (2022). Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis. Acta Neuropathol, 144(3), 413-435. doi:10.1007/s00401-022-02450-3
  • Kluge, A., Bunk, J., Schaeffer, E., Drobny, A., Xiang, W., Knacke, H., Bub, S., Luckstadt, W., Arnold, P., Lucius, R., Berg, D., & Zunke, F. (2022). Detection of neuron-derived pathological alpha-synuclein in blood. Brain, 145(9), 3058-3071. doi:10.1093/brain/awac115
  • Kist, A. M., Breininger, K., Dorrich, M., Durr, S., Schutzenberger, A., & Semmler, M. (2022). A single latent channel is sufficient for biomedical glottis segmentation. Sci Rep, 12(1), 14292. doi:10.1038/s41598-022-17764-1
  • Iannacone, M., Bleriot, C., Andreata, F., Ficht, X., Laura, C., Garcia-Manteiga, J. M., Uderhardt, S., & Ginhoux, F. (2022). Response to contamination of isolated mouse Kupffer cells with liver sinusoidal endothelial cells. Immunity, 55(7), 1141-1142. doi:10.1016/j.immuni.2022.06.012
  • Huang, Y., Bert, C., Sommer, P., Frey, B., Gaipl, U., Distel, L. V., Weissmann, T., Uder, M., Schmidt, M. A., Dorfler, A., Maier, A., Fietkau, R., & Putz, F. (2022). Deep learning for brain metastasis detection and segmentation in longitudinal MRI data. Med Phys, 49(9), 5773-5786. doi:10.1002/mp.15863
  • Gupta, P., Makkar, T. K., Goel, L., & Pahuja, M. (2022). Role of inflammation and oxidative stress in chemotherapy-induced neurotoxicity. Immunol Res, 70(6), 725-741. doi:10.1007/s12026-022-09307-7
  • Gupta, P., Majumdar, A. G., & Patro, B. S. (2022). Non-enzymatic function of WRN RECQL helicase regulates removal of topoisomerase-I-DNA covalent complexes and triggers NF-kappaB signaling in cancer. Aging Cell, 21(6), e13625. doi:10.1111/acel.13625
  • Gunther, C., Winner, B., Neurath, M. F., & Stappenbeck, T. S. (2022). Organoids in gastrointestinal diseases: from experimental models to clinical translation. Gut, 71(9), 1892-1908. doi:10.1136/gutjnl-2021-326560
  • Gerlach, K., Popp, V., Wirtz, S., Al-Saifi, R., Gonzalez Acera, M., Atreya, R., Dregelies, T., Vieth, M., Fichtner-Feigl, S., McKenzie, A. N. J., Rosenbauer, F., Weigmann, B., & Neurath, M. F. (2022). PU.1-driven Th9 Cells Promote Colorectal Cancer in Experimental Colitis Models Through Il-6 Effects in Intestinal Epithelial Cells. J Crohns Colitis, 16(12), 1893-1910. doi:10.1093/ecco-jcc/jjac097
  • Gassner, H., Trutt, E., Seifferth, S., Friedrich, J., Zucker, D., Salhani, Z., Adler, W., Winkler, J., & Jost, W. H. (2022). Treadmill training and physiotherapy similarly improve dual task gait performance: a randomized-controlled trial in Parkinson’s disease. J Neural Transm (Vienna), 129(9), 1189-1200. doi:10.1007/s00702-022-02514-4
  • Furlan, C., Chongdar, N., Gupta, P., Lubitz, W., Ogata, H., Blaza, J. N., & Birrell, J. A. (2022). Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase. Elife, 11. doi:10.7554/eLife.79361
  • Frohlich, K., Knott, M., Hock, S., Dorfler, A., Seifert, F., & Winder, K. (2022). Voxel-wise lesion mapping of restless legs syndrome in multiple sclerosis. Neurol Sci, 43(8), 4953-4959. doi:10.1007/s10072-022-06103-x
  • Frohlich, H., Bontridder, N., Petrovska-Delacreta, D., Glaab, E., Kluge, F., Yacoubi, M. E., Marin Valero, M., Corvol, J. C., Eskofier, B., Van Gyseghem, J. M., Lehericy, S., Winkler, J., & Klucken, J. (2022). Leveraging the Potential of Digital Technology for Better Individualized Treatment of Parkinson’s Disease. Front Neurol, 13, 788427. doi:10.3389/fneur.2022.788427
  • Frech, M., Omata, Y., Schmalzl, A., Wirtz, S., Taher, L., Schett, G., Zaiss, M. M., & Sarter, K. (2022). Btn2a2 Regulates ILC2-T Cell Cross Talk in Type 2 Immune Responses. Front Immunol, 13, 757436. doi:10.3389/fimmu.2022.757436
  • Eisenhut, F., Taha, L., Manhart, M., Thimsen, V., Mantsopoulos, K., Iro, H., Hornung, J., Dorfler, A., & Lang, S. (2022). High-speed flat-detector computed tomography for temporal bone imaging and postoperative control of cochlear implants. Neuroradiology, 64(7), 1437-1445. doi:10.1007/s00234-022-02940-x
  • Drobny, A., Prieto Huarcaya, S., Dobert, J., Kluge, A., Bunk, J., Schlothauer, T., & Zunke, F. (2022). The role of lysosomal cathepsins in neurodegeneration: Mechanistic insights, diagnostic potential and therapeutic approaches. Biochim Biophys Acta Mol Cell Res, 1869(7), 119243. doi:10.1016/j.bbamcr.2022.119243
  • Dinkel, J. G., Lahmer, G., Mennecke, A., Hock, S. W., Richter-Schmidinger, T., Fietkau, R., Distel, L., Putz, F., Dorfler, A., & Schmidt, M. A. (2022). Effects of Hippocampal Sparing Radiotherapy on Brain Microstructure-A Diffusion Tensor Imaging Analysis. Brain Sci, 12(7). doi:10.3390/brainsci12070879
  • Dhikav, V., Jadeja, B., & Gupta, P. (2022). Community Screening of Probable Dementia at Primary Care Center in Western India: A Pilot Project. J Neurosci Rural Pract, 13(3), 490-494. doi:10.1055/s-0042-1750102
  • Collaborators, C.-I., Ma, C., Hanzel, J., Panaccione, R., Sandborn, W. J., D’Haens, G. R., Ahuja, V., Atreya, R., Bernstein, C. N., Bossuyt, P., Bressler, B., Bryant, R. V., Cohen, B., Colombel, J. F., Danese, S., Dignass, A., Dubinsky, M. C., Fleshner, P. R., Gearry, R. B., Hanauer, S. B., Hart, A., Kotze, P. G., Kucharzik, T., Lakatos, P. L., Leong, R. W., Magro, F., Panes, J., Peyrin-Biroulet, L., Ran, Z., Regueiro, M., Singh, S., Spinelli, A., Steinhart, A. H., Travis, S. P., van der Woude, C. J., Yacyshyn, B., Yamamoto, T., Allez, M., Bemelman, W. A., Lightner, A. L., Louis, E., Rubin, D. T., Scherl, E. J., Siegel, C. A., Silverberg, M. S., Vermeire, S., Parker, C. E., McFarlane, S. C., Guizzetti, L., Smith, M. I., Vande Casteele, N., Feagan, B. G., & Jairath, V. (2022). CORE-IBD: A Multidisciplinary International Consensus Initiative to Develop a Core Outcome Set for Randomized Controlled Trials in Inflammatory Bowel Disease. Gastroenterology, 163(4), 950-964. doi:10.1053/j.gastro.2022.06.068
  • Bouhnik, Y., Atreya, R., Casey, D., Gorecki, M., Baik, D., Yoon, S. W., Kwon, T. S., & Jang, M. (2022). Cost-effectiveness Analysis of Subcutaneous Infliximab for Inflammatory Bowel Diseases in Sequential Biologic Treatment. Inflamm Bowel Dis. doi:10.1093/ibd/izac160
  • Besendorf, L., Muller, T. M., Geppert, C. I., Schneider, I., Muhl, L., Atreya, I., Vitali, F., Atreya, R., Neurath, M. F., & Zundler, S. (2022). Vedolizumab blocks alpha4beta7 integrin-mediated T cell adhesion to MAdCAM-1 in microscopic colitis. Therap Adv Gastroenterol, 15, 17562848221098899. doi:10.1177/17562848221098899
  • Becker, E., Schweda, A., Ullrich, K. A., Voskens, C., Atreya, R., Muller, T. M., Atreya, I., Neurath, M. F., & Zundler, S. (2022). Limited Dose-Dependent Effects of Vedolizumab on Various Leukocyte Subsets. Clin Transl Gastroenterol, 13(6), e00494. doi:10.14309/ctg.0000000000000494
  • Becker, E., Dedden, M., Gall, C., Wiendl, M., Ekici, A. B., Schulz-Kuhnt, A., Schweda, A., Voskens, C., Hegazy, A., Vitali, F., Atreya, R., Muller, T. M., Atreya, I., Neurath, M. F., & Zundler, S. (2022). Residual homing of alpha4beta7-expressing beta1(+)PI16(+) regulatory T cells with potent suppressive activity correlates with exposure-efficacy of vedolizumab. Gut, 71(8), 1551-1566. doi:10.1136/gutjnl-2021-324868
  • Battis, K., Florio, J. B., Mante, M., Lana, A., Naumann, I., Gauer, C., Lambrecht, V., Muller, S. J., Cobo, I., Fixsen, B., Kim, H. Y., Masliah, E., Glass, C. K., Schlachetzki, J. C. M., Rissman, R. A., Winkler, J., & Hoffmann, A. (2022). CSF1R-Mediated Myeloid Cell Depletion Prolongs Lifespan But Aggravates Distinct Motor Symptoms in a Model of Multiple System Atrophy. J Neurosci, 42(40), 7673-7688. doi:10.1523/JNEUROSCI.0417-22.2022
  • Balta, D., & Zunke, F. (2022). The role of lysosomes in alpha-synucleinopathies: a focus on glial cells. Neural Regen Res, 17(7), 1486-1488. doi:10.4103/1673-5374.330608
  • Badnaware, S., Srivastava, V. K., Chandel, M., Gupta, P., & Fulzele, P. (2022). Dental and Craniofacial Manifestation of Axenfeld-Rieger Syndrome: A Case Report. Cureus, 14(6), e26442. doi:10.7759/cureus.26442
  • Atreya, R., & Neurath, M. F. (2022). Induction of microRNA-124 as a novel therapeutic concept in ulcerative colitis. Lancet Gastroenterol Hepatol, 7(11), 977-978. doi:10.1016/S2468-1253(22)00249-7